Alzheimer's disease is a progressive mental impairment caused by broad brain degeneration that can strike at any age. It is the most common cause of early senility. The most frequent type of dementia is Alzheimer's disease. This particular irreversible sickness is still being researched by scientists.

The progressive loss of structure and function of neurons is known as neurodegenerative disease. Genetic mutations, such as the common repeat of the CAG nucleotide triplet, aggregation of misfolded proteins, and membrane intracellular systems, such as the protein degradation pathway, all contribute to this. This is an unreversible loss that will result in death. Amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease are examples of neurodegenerative disorders.

The development of a protein peptide known as amyloid beta (beta amyloid, Aß) which clusters into amyloid plaques on the blood cells and on the outside surface of neurons of the brain, which ultimately leads to the killing of neurons are the key events leading to Alzheimer.

Vascular dementia is a decline in thinking skills caused by conditions that block or reduce blood flow to the brain, depriving brain cells of vital oxygen and nutrients Inadequate blood flow can damage and eventually kill cells anywhere in the body. The brain has one of the body's richest networks of blood vessels and is especially vulnerable. In vascular dementia, changes in thinking skills sometimes occur suddenly following strokes that block major brain blood vessels.

Parkinson's disease (PD) is a neurodegenerative disease that influences predominately dopamine-creating neurons in a particular zone of the brain called substantia nigra. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. After diagnosis, treatments can help relieve symptoms, but there is no cure.

Biomarker are biological marker that is an indicator of normal biological processes, pathogenic cycle or pharmacological reactions to a therapeutic treatment.  Biomarkers in Alzheimers are neurochemical indicators used to diagnose the presence of disease. Here, this biological marker helps in identifying the disease in much early state.

Alzheimers disease is usually diagnosed based on the person's medical history, history from relatives, and behavioral observations. The presence of characteristic neurological and neuropsychological features and the absence of alternative conditions is supportive.

Prognosis: Currently there are only few medications for Alzheimer’s and they do not have the power to slow down the symptoms and these medications do not reverse or cure the disease

Risk factors of Alzheimer is not known by scientist, but they have made hypothesis of two known risk factors that is age and genetics. With age, it is identified that 60 % of the people are affected and genetics has also been a major drawback. Other factors are stroke, depression, diabetes, head injury, hypothyroidism and cardiovascular problem. Prevention involves eating a healthy diet, maintaining a good work out routing for body and brain.

Optic neuritis occurs when swelling (inflammation) damages the optic nerve — a bundle of nerve fibers that transmits visual information from your eye to your brain. Common symptoms of optic neuritis include pain with eye movement and temporary vision loss in one eye.

Alzheimer’s disease is perplexing, and it is far-fetched that any one medication or other mediation can effectively treat it. Current approaches concentrate on helping individuals keep up mental health, oversee behavioral indications, and moderate or postpone the side effects of sickness. Scientists plan to create treatments focusing on hereditary, sub-atomic, and cell systems so the genuine hidden reason for the infection can be ceased or forestalled.

To delay or prevent Alzheimer’s disease a lot of herbal cures, dietary supplements, and therapeutic nourishment are promoted as memory enhancers or medications. Claims about the safety and effectiveness of these products.

People who help the diseased people with their day to day routine, being a companion in sharing their day. Most of the people become aggressive and uncontrollable, in this case, the family seeks the help of home cares and caretakers. They are specially trained people who have the ability to take care of them. They even go to an extent to conduct social events so as to strip off their ideology of isolation.

Animal models for Alzheimers disease is important to consider the human phenotype and what is being demonstrated regarding the animal phenotype. Bradley Hyman, Faculty of neuroscience at Harvard Medical School, said that animal models of Alzheimer’s disease, based on the genetics of the disease and the closely related frontotemporal dementia, replicate at least some of the pathology. Analysts have been effective at demonstrating quite certain parts of Alzheimer's illness in the mouse (e.g., plaques, tangles).

Alzheimers 2019 objective is to bring all existing and budding bio entrepreneurs together to share present and experiences new challenges and innovations in Alzheimers & Dementia community. Every year, over a million companies are started in the world with about 5–10 of them known as high technology companies. Changing ideas into business ventures is tricky opportunity-recognition step critical in new venture creation. Even though life scientists are the founders of biotech companies, studies have shown that most successful high tech start-ups are founded by a team of two to three individuals with mixed backgrounds, substantial industry experience and a very clear market and product focus at founding. This two days conference will be a highly interactive forum that will bring experts in areas ranging from Alzheimer's disease analysis to novel therapeutic techniques and approaches to cure Alzheimer disease. Our outstanding speakers will do talks for 25-30 min and Students do poster presentations from submitted abstracts. Interested business candidates will exhibit their products and some do Workshops.